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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Mike Brown | 243 | 2009-2020 | |
| 2 | Lúcio García | 239 | 2016-2023 | |
| 3 | Tommy Bourassa | 144 | 2016-2023 | |
| 4 | Gabriel Miranda | 128 | 2014-2027 | |
| 5 | António Castillo | 125 | 2010-2020 | |
| 6 | Bill Starr# | 119 | 2031-2034 | |
| 7 | Pete Smith | 115 | 2021-2026 | |
| 8 | Manuel Domínguez | 98 | 2013-2016 | |
| 8 | Tom Mullins | 98 | 2021-2025 | |
| 10 | Merrill Erickson | 97 | 2029-2031 | |
| 10 | Pedro Rodríguez | 97 | 2019-2021 | |
| 12 | Hamilton Hughes | 96 | 2027-2032 | |
| 12 | Scott MacDonald | 96 | 2011-2016 | |
| 14 | Dave Dawson | 92 | 2014-2024 | |
| 14 | Miguel Rosa | 92 | 2016-2020 | |
| 16 | Chang-geun Kim | 88 | 2014-2021 | |
| 17 | Paul Miller | 85 | 2017-2019 | |
| 17 | Jorge Sáenz | 85 | 2015-2019 | |
| 19 | Javier Peńa | 84 | 2023-2027 | |
| 19 | Leonardo Torres# | 84 | 2032-2038 | |
| 21 | Eichiro Yamamoto | 83 | 2018-2021 | |
| 22 | Marc May | 81 | 2018-2020 | |
| 22 | Juan Rodríguez | 81 | 2010-2015 | |
| 24 | David Winters | 79 | 2013-2019 | |
| 25 | Trevor Mitchell | 78 | 2010-2019 | |
| 25 | Luther Stoffels | 78 | 2020-2025 | |
| 27 | Félix Gonzáles | 77 | 2027-2028 | |
| 28 | Alejandro Fernández# | 75 | 2037-2038 | |
| 29 | Dennis Garner# | 74 | 2031-2035 | |
| 29 | Pancho Juárez | 74 | 2007-2010 | |
| 29 | Mario Ramírez | 74 | 2014-2017 | |
| 32 | John Cunningham# | 73 | 2034-2038 | |
| 32 | Todd Smith | 73 | 2020-2025 | |
| 34 | Jack Cartwright | 72 | 2010-2019 | |
| 34 | Dale Winters | 72 | 2029-2034 | |
| 36 | Henning Huisman | 70 | 2019-2029 | |
| 36 | Juan Paredes | 70 | 2010-2012 | |
| 38 | Manuel Chávez | 68 | 2010-2011 | |
| 39 | Derrick van Zelst | 66 | 2013-2016 | |
| 40 | Vicente Ricks | 65 | 2016-2019 | |
| 40 | Brody Sexton# | 65 | 2035-2038 | |
| 42 | Mal Snyder | 64 | 2020-2023 | |
| 43 | Rob DeWitt | 62 | 2029-2035 | |
| 44 | Lu-fang Huie | 61 | 2016-2024 | |
| 44 | Danny Reed | 61 | 2016-2021 | |
| 46 | Tony Martínez# | 60 | 2034-2035 | |
| 47 | Nick Davis | 59 | 2016-2018 | |
| 47 | Edgardo Gonzáles | 59 | 2010-2012 | |
| 49 | Mario Vélez# | 58 | 2035-2037 | |
| 49 | Steve Welch# | 58 | 2031-2038 | |
| 51 | Jesús Carrillo | 57 | 2008-2020 | |
| 52 | Enrique Cortéz | 56 | 2020-2023 | |
| 52 | Dominic Swift# | 56 | 2035-2038 | |
| 54 | Augusto Baca# | 55 | 2026-2029 | |
| 54 | Ben Dougherty | 55 | 2024-2026 | |
| 54 | Ryan Hensley | 55 | 2015-2017 | |
| 54 | Richard Hinkle | 55 | 2027-2028 | |
| 54 | Carlos Holguín | 55 | 2011-2013 | |
| 54 | Juan Mendoza | 55 | 2017-2018 | |
| 54 | Yoshihide Takahashi | 55 | 2015-2017 | |
| 61 | Chris Austin | 54 | 2025-2028 | |
| 61 | Felipe Castro# | 54 | 2028-2032 | |
| 61 | Rodrigo Pérez# | 54 | 2028-2036 | |
| 61 | Júlio Rodríguez# | 54 | 2029-2032 | |
| 65 | Javier Morales# | 53 | 2031-2034 | |
| 66 | Mauro Díaz | 52 | 2028-2031 | |
| 66 | Frank Martínez | 52 | 2027-2031 | |
| 66 | Miguel Price | 52 | 2032-2034 | |
| 66 | Desi Thompson | 52 | 2024-2026 | |
| 70 | Tony Abete | 51 | 2018-2022 | |
| 70 | Jeff Doss | 51 | 2020-2024 | |
| 70 | Wilson Gonzáles | 51 | 2013-2023 | |
| 70 | Arthur Guzmán# | 51 | 2033-2036 | |
| 70 | Vincent Hobbs | 51 | 2011-2013 | |
| 70 | Daniel Robert | 51 | 2015-2017 | |
| 70 | Don Thomas | 51 | 2022-2026 | |
| 70 | Lawrence Yates | 51 | 2019-2022 | |
| 78 | Juan Colón# | 50 | 2035-2035 | |
| 78 | Pedro Fuentes | 50 | 2016-2018 | |
| 78 | Miguel Montés | 50 | 2014-2017 | |
| 78 | Tony Parker | 50 | 2025-2028 | |
| 78 | Ernesto Román | 50 | 2010-2012 | |
| 78 | Steve Sparks# | 50 | 2036-2038 | |
| 84 | Dewitt Jacobson# | 49 | 2037-2038 | |
| 84 | Miguel Martínez# | 49 | 2031-2038 | |
| 84 | Guang Miao# | 49 | 2031-2036 | |
| 84 | Damon Mitchell | 49 | 2013-2015 | |
| 84 | Ian Oliver | 49 | 2015-2017 | |
| 84 | José Ortíz | 49 | 2015-2017 | |
| 84 | Jean-Paul St-Pierre | 49 | 2015-2024 | |
| 91 | Weston Chaney | 48 | 2027-2029 | |
| 91 | Geoff May# | 48 | 2033-2035 | |
| 91 | Jesús Ontiveros | 48 | 2010-2013 | |
| 91 | Ron Winston# | 48 | 2030-2034 | |
| 95 | Kosho Kichikawa | 47 | 2012-2015 | |
| 95 | Don Soper | 47 | 2022-2027 | |
| 97 | Jared Anderson# | 46 | 2037-2038 | |
| 97 | Luis Rincón# | 46 | 2030-2037 | |
| 97 | Neal Sánchez# | 46 | 2032-2034 | |
| 97 | Wilson Turner# | 46 | 2030-2036 |
