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| Monday, February 27th , 2051 |
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| Promoted CL Luis Díaz to Major League Cozumel. |
| Promoted RF Ricardo Ladaotina to Major League Cozumel. |
| Promoted 2B Ángel Águila to Major League Cozumel. |
| Promoted RF Joe Spencer to Major League Cozumel. |
| Promoted LF Harris Lucas to Major League Cozumel. |
| Thursday, December 29th , 2050 |
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| Placed SP Merlin Peterson on the active roster. |
| Sunday, December 4th , 2050 |
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| 2B Zi-xing Shao becomes a free-agent. |
| Thursday, June 16th , 2050 |
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| Promoted RF Ricardo Reyes to Major League Colorado. |
| Promoted CF Bayani Diloy to Major League Colorado. |
| Promoted SP Mark Valenzuela to Triple A Mexico City. |
| Received RP Mike Broadley from Triple A Mexico City. |
| Received RF Ricardo Ladaotina from Major League Colorado. |
| Received 2B Ángel Águila from Major League Colorado. |
| Received SP Edward Petty from Class A Colorado. |
| Demoted RP Miguel López to Rookie League Logan. |
| Monday, June 13th , 2050 |
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| Received RP Miguel López from Triple A Mexico City. |
| Activated CF Jesús Ibarra from the injured list. |
| Monday, June 6th , 2050 |
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| Promoted RP Mike Walters to Triple A Mexico City. |
| Promoted RP Mike Broadley to Triple A Mexico City. |
| Received RP David James from Triple A Mexico City. |
| Received SP Mark Valenzuela from Triple A Mexico City. |
| Placed SP Merlin Peterson on the 7-day injured list, retroactive to 06/04/2050. |
| Placed CF Jesús Ibarra on the 7-day injured list, retroactive to 06/05/2050. |
| Received 2B Zi-xing Shao from Triple A Mexico City. |
| Monday, May 30th , 2050 |
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| Promoted RP William Garza to Triple A Mexico City. |
| Promoted CF Bai-luo Moy to Triple A Mexico City. |
| Received RF Ricardo Reyes from Triple A Mexico City. |
| Received SS Miguel Herrera from Class A Colorado. |
| Monday, May 23rd , 2050 |
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| Promoted SP Mark Valenzuela to Triple A Mexico City. |
| Received SP Merlin Peterson from Triple A Mexico City. |
| Monday, May 16th , 2050 |
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| Promoted CL Héctor Díaz to Triple A Mexico City. |
| Received SP William Garza from Triple A Mexico City. |
| Received RP Mike Broadley from Triple A Mexico City. |
| Received RP Luis Díaz from Class A Colorado. |
| Demoted SP Tom Green to Class A Colorado. |
| Demoted SS Miguel Herrera to Class A Colorado. |
| Promoted RP David James to Triple A Mexico City. |
| Promoted RF Ricardo Reyes to Triple A Mexico City. |
| Received SP Tom Green from Class A Colorado. |
| Received LF Harris Lucas from Class A Colorado. |
| Monday, May 2nd , 2050 |
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| Promoted SP Wendell Johnston to Triple A Mexico City. |
| Promoted RP William Garza to Triple A Mexico City. |
| Promoted RP Mike Broadley to Triple A Mexico City. |
| Promoted 3B John Schneider to Triple A Mexico City. |
| Received SP Ryan Rigney from Triple A Mexico City. |
| Received SS José Pérez from Class A Colorado. |
| Received SP Tom Green from Class A Colorado. |
| Received SP Paul von Wilke from Class A Colorado. |
| Received SS Miguel Herrera from Class A Colorado. |
| Demoted RP Blair Moore to Class A Colorado. |
| Received RP Héctor Díaz from Triple A Mexico City. |
| Received RP David James from Triple A Mexico City. |
| Received SP Ron Kelley from Triple A Mexico City. |
| Demoted SP Edward Petty to Class A Colorado. |
| Demoted RP Paul von Wilke to Class A Colorado. |
| Demoted CL Jason Ewing to Class A Colorado. |
| Monday, April 18th , 2050 |
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| Promoted RP David James to Triple A Mexico City. |
| Promoted SP Ron Kelley to Triple A Mexico City. |
| Promoted RP Ryan Rigney to Triple A Mexico City. |
| Promoted SS George Palmer to Triple A Mexico City. |
| Received SP Mike Broadley from Triple A Mexico City. |
| Received SP Mark Valenzuela from Triple A Mexico City. |
| Received CL Jason Ewing from Triple A Mexico City. |
| Received SP Blair Moore from Class A Colorado. |
| Monday, April 4th , 2050 |
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| Promoted RP Tony French to Triple A Mexico City. |
| Promoted RP John Drier to Triple A Mexico City. |
| Received RP William Garza from Triple A Mexico City. |
| Received RP David James from Triple A Mexico City. |
| Received RP Dave Hudson from Class A Colorado. |
| Received SP Wendell Johnston from Triple A Mexico City. |
| Received C Dan Bonner from Triple A Mexico City. |
| Received C Gil Ortíz from Class A Colorado. |
| Received 1B Ryan Myers from Triple A Mexico City. |
| Received CF Bayani Diloy from Triple A Mexico City. |
| Received SS Culley Palmer from Class A Colorado. |
| Received RF Ricardo Reyes from Triple A Mexico City. |
| Received RF Joe Spencer from Triple A Mexico City. |
| Demoted SP Tom Green to Class A Colorado. |
| Demoted SS Miguel Herrera to Class A Colorado. |
| Demoted SS Francisco Martínez to Class A Colorado. |
| Demoted LF Harris Lucas to Class A Colorado. |
| Monday, February 28th , 2050 |
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| Promoted RF Ricardo Reyes to Major League Colorado. |
| Promoted CF Joe Cole to Major League Colorado. |
| Promoted CF Bayani Diloy to Major League Colorado. |
| Promoted RF Joe Spencer to Major League Colorado. |
| Promoted C Dan Bonner to Major League Colorado. |
| Thursday, January 20th , 2050 |
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| Signed Hitting Coach Greg Schultz. |
| Thursday, November 25th , 2049 |
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| Signed Pitching Coach Allen King. |
| Monday, September 20th , 2049 |
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| Activated SP Ray Banks from the injured list. |
| Activated SP Cong Seah from the injured list. |
| Activated SP Ryan Rigney from the injured list. |
| Activated SP Mike Walters from the injured list. |
