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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Gary Grimes | 304 | 2024-2035 | |
| 2 | Neil Snow | 286 | 2029-2037 | |
| 3 | Francisco López | 280 | 2007-2020 | |
| 4 | Rusty van Rhee | 267 | 2027-2037 | |
| 5 | Quincy Robinson | 261 | 2011-2022 | |
| 6 | Bob Ford# | 254 | 2039-2049 | |
| 7 | Ed Campbell# | 253 | 2042-2049 | |
| 8 | Jorge Salazar | 233 | 2018-2027 | |
| 9 | Félix Medina | 227 | 2018-2026 | |
| 10 | Ángel Rodríguez | 212 | 2013-2023 | |
| 11 | Craig Hoover# | 211 | 2039-2049 | |
| 12 | Gaspare Marletti | 208 | 2036-2046 | |
| 12 | Okura Oike | 208 | 2014-2029 | |
| 14 | José Cuellar | 207 | 2031-2040 | |
| 14 | Sandro Gonzáles | 207 | 2017-2031 | |
| 14 | Yodo Nakagawa | 207 | 2017-2030 | |
| 17 | Sergio Hernández | 202 | 2033-2042 | |
| 18 | Bobby Lawrence | 199 | 2018-2025 | |
| 19 | Héctor Negrón | 198 | 2019-2029 | |
| 20 | Pepe Fernández | 197 | 2017-2028 | |
| 21 | Juan Medina | 194 | 2013-2020 | |
| 22 | Mel Oliver# | 190 | 2041-2049 | |
| 23 | Joe Hopkins | 185 | 2027-2037 | |
| 24 | Dave Carbone | 181 | 2017-2030 | |
| 24 | Miguel Rodríguez | 181 | 2011-2018 | |
| 24 | R.J. Watkins | 181 | 2010-2020 | |
| 27 | Javier Santos | 177 | 2037-2044 | |
| 28 | Sam Olson | 174 | 2032-2038 | |
| 28 | Takaaki Omori | 174 | 2017-2028 | |
| 30 | Darby Noftle | 170 | 2011-2023 | |
| 31 | Jonas Malaret | 169 | 2017-2026 | |
| 32 | Alonso Delgado | 168 | 2033-2044 | |
| 33 | Eddy Buckley | 167 | 2010-2016 | |
| 34 | Juan Aguilar | 166 | 2014-2028 | |
| 35 | Daniel Carter | 165 | 2032-2037 | |
| 36 | Felipe Téllez | 164 | 2016-2029 | |
| 37 | Dave Lewis | 163 | 2012-2022 | |
| 37 | Zach Montgomery# | 163 | 2042-2049 | |
| 39 | Dave Barrett# | 162 | 2043-2049 | |
| 39 | John Smith | 162 | 2023-2031 | |
| 41 | Clayton Patton | 161 | 2010-2020 | |
| 42 | Rob Price | 159 | 2028-2036 | |
| 42 | Ron Simmons | 159 | 2030-2041 | |
| 42 | Stanley Wise | 159 | 2031-2037 | |
| 45 | Mike Doss | 157 | 2024-2034 | |
| 46 | Pancho Guerrero | 156 | 2030-2035 | |
| 46 | Will Huggins | 156 | 2016-2030 | |
| 48 | Don Wiggins | 155 | 2027-2035 | |
| 49 | Chris Chamberlain | 153 | 2027-2036 | |
| 49 | Manuel González | 153 | 2020-2029 | |
| 49 | Chad Hall# | 153 | 2041-2049 | |
| 49 | Pedro Valdés | 153 | 2024-2032 | |
| 53 | John Allen | 151 | 2032-2045 | |
| 54 | Rusty Jones# | 150 | 2041-2049 | |
| 55 | Manuel González | 149 | 2028-2040 | |
| 55 | Myron Hawkins | 149 | 2010-2023 | |
| 55 | Ray McIntyre | 149 | 2026-2037 | |
| 55 | Sancho Valdéz | 149 | 2007-2017 | |
| 59 | Drew Payne# | 147 | 2044-2049 | |
| 60 | Robert Spencer | 146 | 2007-2017 | |
| 61 | Derrick Harrison | 144 | 2007-2024 | |
| 62 | Alberto Galindo | 143 | 2029-2044 | |
| 63 | Irving Baker | 142 | 2010-2021 | |
| 64 | Carlos Díaz | 140 | 2021-2029 | |
| 64 | Carlos Martínez | 140 | 2038-2049 | |
| 66 | Walt Barry | 139 | 2037-2047 | |
| 67 | Christiano Bray | 138 | 2033-2046 | |
| 68 | Beau Montgomery | 136 | 2029-2035 | |
| 68 | Ben Sweeny | 136 | 2014-2017 | |
| 70 | Carlos García | 135 | 2018-2030 | |
| 70 | Danny Myers | 135 | 2010-2016 | |
| 70 | Hyun-soo Yun | 135 | 2011-2017 | |
| 73 | Ray Johnston | 133 | 2027-2038 | |
| 74 | Walt Núñez | 132 | 2039-2045 | |
| 75 | Mario Chávez | 131 | 2019-2032 | |
| 75 | Javier García | 131 | 2018-2033 | |
| 77 | Joo-hyun Chong | 130 | 2018-2023 | |
| 77 | John Humphrey | 130 | 2007-2017 | |
| 77 | Ron Jenkins | 130 | 2030-2035 | |
| 77 | José Padilla | 130 | 2030-2038 | |
| 81 | Tony Anson# | 129 | 2040-2049 | |
| 81 | Clarence Skerratt | 129 | 2021-2032 | |
| 83 | Ivo Estima | 128 | 2011-2020 | |
| 83 | Jorge Rivera# | 128 | 2039-2049 | |
| 83 | Manny Rivera | 128 | 2010-2021 | |
| 86 | Michael Puckett | 127 | 2018-2026 | |
| 87 | Darren Blackwell | 126 | 2025-2037 | |
| 87 | Ramiro López# | 126 | 2047-2049 | |
| 87 | José Morán | 126 | 2022-2034 | |
| 90 | John Murphy# | 125 | 2043-2049 | |
| 90 | Barrett Pritchard | 125 | 2035-2041 | |
| 92 | Valentin Cuny | 124 | 2041-2046 | |
| 92 | Orlando Díaz | 124 | 2024-2032 | |
| 92 | Carlos Fernández | 124 | 2016-2029 | |
| 92 | Kevin Richards | 124 | 2037-2049 | |
| 92 | Dan Rogers | 124 | 2022-2034 | |
| 97 | Clarence Holmes | 123 | 2033-2042 | |
| 97 | Ramón López | 123 | 2017-2030 | |
| 99 | Javier Duarte | 122 | 2025-2030 | |
| 99 | Gilberto Guzmán | 122 | 2039-2047 |
