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| Monday, February 27th , 2051 |
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| Promoted 1B Alberto Esquivel to Major League Greenville. |
| Monday, April 4th , 2050 |
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| Promoted SP Adam Garland to Triple A New England. |
| Promoted SP Dan Bush to Double A Minnesota . |
| Promoted SP Myles Walker to Double A Minnesota . |
| Promoted SP Adrián Chávez to Double A Minnesota . |
| Promoted RP Chance Crews to Double A Minnesota . |
| Promoted CL Jonathan Simons to Double A Minnesota . |
| Promoted C Tony López to Double A Minnesota . |
| Promoted CF Ángel López to Double A Minnesota . |
| Promoted LF Brian Moran to Double A Minnesota . |
| Promoted RF Alonso Anuncivais to Double A Minnesota . |
| Promoted 2B Bo Pérez to Double A Minnesota . |
| Promoted 1B Joe Dale to Double A Minnesota . |
| Promoted 3B Pat Johnson to Double A Minnesota . |
| Promoted 2B Alberto Chávez to Double A Minnesota . |
| Promoted C Júlio García to Double A Minnesota . |
| Promoted CL Howard Mullins to Double A Minnesota . |
| Promoted CF Tomás Medina to Double A Minnesota . |
| Received SP Gertrudes Remgio from Rookie League Birmingham. |
| Received CL Sam Mitchell from Double A Minnesota . |
| Received SP Ottavio Gabriel from Rookie League Birmingham. |
| Received SP Juan Gutiérrez from Rookie League Birmingham. |
| Received SP Jim Quezada from Rookie League Birmingham. |
| Received SP António Lugo from Rookie League Birmingham. |
| Received 1B Alberto Esquivel from Rookie League Birmingham. |
| Received SS Tony Tirado from Rookie League Birmingham. |
| Received 1B Peto Osayande from Rookie League Birmingham. |
| Received CF Michael Curry from Rookie League Birmingham. |
| Received SS Octávio Téllez from Rookie League Birmingham. |
| Received LF Jesús Mendoza from Rookie League Birmingham. |
| Received SP José Mata from Rookie League Birmingham. |
| Received SS Augusto Ayala from Rookie League Birmingham. |
| Received CF Mike Kennedy from Rookie League Birmingham. |
| Received SP Tommy Miller from Rookie League Birmingham. |
| Received SP Juan Ramírez from Rookie League Birmingham. |
| Sunday, November 14th , 2049 |
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| 2B Akaday Mkwasi retired from professional baseball. |
| RP Curt Irwin retired from professional baseball. |
| LF Ángel Pérez retired from professional baseball. |
| SP Jesús Cedeño retired from professional baseball. |
